Solvent-Free Microwave Synthesis of Aryloxypropanolamines by Ring Opening of Aryloxy Epoxides | Zendy

Rukhsana I. Kureshy | Zendy; Irshad Ahmad | Zendy; Kavita Pathak | Zendy; Noorul H. Khan | Zendy; Sayed H. R. Abdi | Zendy; Hari C. Bajaj | Zendy; Eringathodi Suresh | Zendy

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Solvent-Free Microwave Synthesis of Aryloxypropanolamines by Ring Opening of Aryloxy Epoxides

Author(s) -

Rukhsana I. Kureshy,

Irshad Ahmad,

Kavita Pathak,

Noorul H. Khan,

Sayed H. R. Abdi,

Hari C. Bajaj,

Eringathodi Suresh

Publication year - 2009

Publication title -

research letters in organic chemistry

Language(s) - English

Resource type - Journals

eISSN - 1687-6938

pISSN - 1687-6865

DOI - 10.1155/2009/109717

Subject(s) - isopropylamine , yield (engineering) , ring (chemistry) , solvent , microwave , microwave irradiation , chemistry , organic chemistry , nuclear chemistry , materials science , catalysis , composite material , physics , quantum mechanics

The ring opening reaction of aryloxyepoxides with isopropylamine under solvent-free microwave irradiation produced therapeutically useful -blockers-aryloxypropanolamines in excellent yield (up to 98%) in 10 minutes which is considerably less than the time taken in classical heating (∼16 hours)

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