Marie Curie – Genome Architecture in Relation to Disease Conference 3 Higher Order Genome Architecture

This conference is the final part of our series of meetings entitled “Genome Architecture in Relation to Disease”. A major part of these meetings is to introduce junior researchers to new topics and new ideas. The previous series focussed on genetics and the use of microarrays for investigating genetic variations and abnormalities. In this series we wanted the topics to evolve from thinking of the genome in a “linear” format (Conference 1: Molecular profiling of the genome) to considering the genetic and epigenetic factors responsible for controlling gene expression (Conference 2: Interplay among genetics, epigenetics and non-coding RNAs). Finally, we wanted to place this “linear” genome into the context of a nucleus and to show how the genome architecture is able to influence gene expression.