Elevation in Peripheral Blood Circulating Tumor Cell Number Correlates with Macroscopic Progression in UICC Stage IV Colorectal Cancer Patients
Author(s) -
Béla Molnár,
Lajos Flóró,
Ferenc Sípos,
Bernadett Tóth,
L Sréter,
Zsolt Tulassay
Publication year - 2008
Publication title -
disease markers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.912
H-Index - 66
eISSN - 1875-8630
pISSN - 0278-0240
DOI - 10.1155/2008/941509
Subject(s) - circulating tumor cell , medicine , colorectal cancer , cytokeratin , peripheral blood , tumor progression , oncology , cancer , stage (stratigraphy) , peripheral , gastroenterology , pathology , metastasis , biology , immunohistochemistry , paleontology
Cytokeratin(CK) based real-time RT-PCR assays (QRT-PCR) are now available for peripheral blood circulating tumor cell (CTC) evaluations in colorectal cancer(CRC) patients. Results are non-existent for the application of these techniques to the determination of progression and therapy response in Dukes stage D CRC patients.
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