Synthesis and Antimicrobial Activity of Some Chalcone Derivatives | Zendy

Y. Rajendra Prasad | Zendy; A. Lakshmana Rao | Zendy; R. Rambabu | Zendy

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Synthesis and Antimicrobial Activity of Some Chalcone Derivatives

Author(s) -

Y. Rajendra Prasad,

A. Lakshmana Rao,

R. Rambabu

Publication year - 2007

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2008/876257

Subject(s) - chalcone , antimicrobial , chemistry , traditional medicine , combinatorial chemistry , stereochemistry , organic chemistry , medicine

In an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of aqueous solution of potassium hydroxide and ethanol at room temperature. The synthesized compounds were characterized by means of their IR, 1H-NMR spectral data and elemental analysis. All the compounds were tested for their antibacterial and antifungal activities by the cup plate method

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