Association between Proton Pump Inhibitors and Respiratory Infections: A Systematic Review and Meta-Analysis of Clinical Trials
Author(s) -
Nabil Sultan,
José Nazareno,
James C. Gregor
Publication year - 2008
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/2008/821385
Subject(s) - medicine , esomeprazole , omeprazole , meta analysis , pantoprazole , proton pump inhibitor , placebo , adverse effect , randomized controlled trial , respiratory system , rabeprazole , gastroenterology , pathology , alternative medicine
Proton pump inhibitors (PPIs) have become the mainstay of treatment for and prevention of many serious gastrointestinal diseases. Laboratory and clinical evidence suggests that the increase in gastric pH caused by PPIs may be linked to increased bacterial colonization of the stomach and may predispose patients to an increased risk for respiratory infections.
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