Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients | Zendy

Ferdinando Mannello | Zendy; Laura Fabbri | Zendy; Eleonora Ciandrini | Zendy; Gaetana A. Tonti | Zendy

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Increased Levels of Erythropoietin in Nipple Aspirate Fluid and in Ductal Cells from Breast Cancer Patients

Author(s) -

Ferdinando Mannello,

Laura Fabbri,

Eleonora Ciandrini,

Gaetana A. Tonti

Publication year - 2008

Publication title -

analytical cellular pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.576

H-Index - 24

eISSN - 2210-7185

pISSN - 2210-7177

DOI - 10.1155/2008/812193

Subject(s) - erythropoietin , breast cancer , medicine , cancer , oncology , pathology

Erythropoietin (Epo) is an important regulator of erythropoiesis, and controls proliferation and differentiation of both erythroid and non-erythroid tissues. Epo is actively synthesized by breast cells during lactation, and also plays a role in breast tissues promoting hypoxia-induced cancer initiation. Our aims are to perform an exploratory investigation on the Epo accumulation in breast secretions from healthy and cancer patients and its localization in breast cancer cells.

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