Fatal Disseminated Trichosporon asahii Infection in a Child with Acute Lymphoblastic Leukemia | Zendy

Roseline Thibeault | Zendy; Martin Champagne | Zendy; Louis de Repentigny | Zendy; JeanChristophe Fournet | Zendy; Bruce Tapiéro | Zendy; Albert Moghrabi | Zendy; Philippe Ovetchkine | Zendy

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Fatal Disseminated Trichosporon asahii Infection in a Child with Acute Lymphoblastic Leukemia

Author(s) -

Roseline Thibeault,

Martin Champagne,

Louis de Repentigny,

JeanChristophe Fournet,

Bruce Tapiéro,

Albert Moghrabi,

Philippe Ovetchkine

Publication year - 2007

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/2008/787689

Subject(s) - voriconazole , trichosporon , lymphoblastic leukemia , autopsy , medicine , leukemia , immunology , antifungal , biology , dermatology , genetics , yeast

Few cases of Trichosporon species infection have been reported in children. The present report describes a case of fatal disseminated Trichosporon asahii infection in a child treated for relapsed leukemia. Voriconazole has previously shown promising activity in vitro, and has been used successfully in the treatment of T asahii infections. The patient died five days after voriconazole treatment was started, and the autopsy revealed widespread systemic dissemination to all organs.

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