Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis | Zendy

Paola Barboro | Zendy; A. Rubagotti | Zendy; Paola Orecchia | Zendy; Bruno Spina | Zendy; Mauro Truini | Zendy; Erica Repaci | Zendy; G. Carmignani | Zendy; Andrea Romagnoli | Zendy; Carlo Introini | Zendy; Francesco Boccardo | Zendy; Barbara Carnemolla | Zendy; Cecilia Balbi | Zendy

Open Access

Differential Proteomic Analysis of Nuclear Matrix in Muscle-Invasive Bladder Cancer: Potential to Improve Diagnosis and Prognosis

Author(s) -

Paola Barboro,

A. Rubagotti,

Paola Orecchia,

Bruno Spina,

Mauro Truini,

Erica Repaci,

G. Carmignani,

Andrea Romagnoli,

Carlo Introini,

Francesco Boccardo,

Barbara Carnemolla,

Cecilia Balbi

Publication year - 2008

Publication title -

analytical cellular pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.576

H-Index - 24

eISSN - 2210-7185

pISSN - 2210-7177

DOI - 10.1155/2008/686940

Subject(s) - bladder cancer , proteome , western blot , biology , phenotype , proteomics , cancer , pathology , immunohistochemistry , nuclear matrix , cancer research , medicine , bioinformatics , genetics , gene , chromatin

Although several molecular markers for bladder cancer have been identified, at present little information on prognostic biomarkers is available in the literature. Prognostication of this tumor is largely based on clinicopathological characteristics. Our aim was to identify nuclear matrix (NM) proteins that might serve to better characterize the phenotype of the invasive bladder cancer and to investigate their diagnostic and prognostic roles.

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