Open AccessSynthesis and Antimicrobial Studies of a New Series of Bis-Heterocycles
Author(s) -
B. Jayashankara,
K. M. Lokanatha
Publication year - 2007
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2008/659752
Subject(s) - antimicrobial , imidazole , carbon 13 nmr , chemistry , proton nmr , elemental analysis , combinatorial chemistry , organic chemistry , stereochemistry
Series of novel bis-heterocycles bearing isoxazoline and imidazole moieties have been synthesized via 1,3-dipolarcycloaddition reactions. (1)HNMR, (13)CNMR, IR and elemental analyses characterized the newly synthesized compounds. All the synthesized compounds were evaluated for their antimicrobial activity and were compared with the standard drugs. The compounds demonstrated potent to weak antimicrobial activity
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