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Synthesis, Characterization and Antimicrobial Studies of 3-[(2-Hydroxy-quinolin-3-ylmethylene)-amino]-2-phenyl-3H-quinazolin-4-one and its Metal(II) Complexes
Author(s) -
K. Siddappa,
Tukaram Reddy,
M. Mallikarjun,
C. V. Reddy
Publication year - 2007
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2008/659386
Subject(s) - antimicrobial , chemistry , characterization (materials science) , metal , combinatorial chemistry , stereochemistry , organic chemistry , nanotechnology , materials science
A new complexes of the type ML2 and M′L [where M=Cu(II), Co(II), and Ni(II) and M′= Zn(II), Cd(II) and Hg(II)]. L = 3-[(2-hydroxy-quinolin-3-ylmethylene)-amino]-2-phenyl-3 H -quinazolin-4-one, (HQMAPQ) Schiff base have been synthesized and characterized by elemental analysis, magnetic susceptibility, molar conductance, IR, 1 H NMR, UV-Visible and ESR data. The studies indicate the HQMAPQ acts as doubly monodentate bridge for metal(II) ions and form mononuclear complexes. The complexes Ni(II), Co(II) and Cu(II) complexes are found to be octahedral, where as Zn(II), Cd(II) and Hg(II) complexes are four coordinated with tetrahedral geometry. The synthesized ligand and its metal(II) complexes were screened for their antimicrobial activity.

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