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Fibronectin Adsorption to Nanopatterned Silicon Surfaces
Author(s) -
Ildar Salakhutdinov,
Pamela J. VandeVord,
Olena Palyvoda,
Howard W.T. Matthew,
G. Tatagiri,
Hitesh Handa,
Guangzhao Mao,
Gregory W. Auner,
Golam Newaz
Publication year - 2008
Publication title -
journal of nanomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.463
H-Index - 66
eISSN - 1687-4129
pISSN - 1687-4110
DOI - 10.1155/2008/543170
Subject(s) - fibronectin , materials science , adsorption , nanoscopic scale , surface (topology) , silicon , nanotechnology , diffraction , molecule , grating , optics , optoelectronics , cell , organic chemistry , chemistry , geometry , biochemistry , mathematics , physics
The possibility of using surface topography for guidance of different biological molecules and cells is a relevant topic that can be applied to a wide research activity. This study investigated the adsorption of fibronectin to a diffraction grated silicon surface. The rectangular grating profile featured a controlled surface with 350 nm period and a corrugation depth of 90 nm. Results demonstrated that the controlled surface had a significantly positive effect on the fibronectin binding. Thus, nanoscale surface topography can enhance fibronectin binding

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