New Complex Chromosomal Translocation in Chronic Myeloid Leukaemia: t(9;18;22)(q34;p11;q11) | Zendy

Abdeljabar El Andaloussi | Zendy; Chrystèle BilhouNabera | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

New Complex Chromosomal Translocation in Chronic Myeloid Leukaemia: t(9;18;22)(q34;p11;q11)

Author(s) -

Abdeljabar El Andaloussi,

Chrystèle BilhouNabera

Publication year - 2007

Publication title -

journal of biomedicine and biotechnology

Language(s) - English

Resource type - Journals

eISSN - 1110-7251

pISSN - 1110-7243

DOI - 10.1155/2007/92385

Subject(s) - chromosomal translocation , fluorescence in situ hybridization , karyotype , chronic myeloid leukaemia , myeloid leukemia , cytogenetics , medicine , fish <actinopterygii> , biology , cancer research , chromosome , genetics , gene , fishery

A Chronic myeloid leukaemia (CML) case with a new complex t(9;18;22)(q34;p11;q11) of a 29-year-old man is being reported. For the first time, this translocation has been characterized by karyotype complemented with fluorescence in situ hybridization (FISH). In CML, the complex and standard translocations have the same prognosis. The patient was treated with standard initial therapy based on hydroxyurea before he died due to heart failure four months later. Our finding indicates the importance of combined cytogenetic analysis for diagnosis and guidance of treatment in clinical diagnosis of CML

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research