Role of PPARs and Retinoid X Receptors in the Regulation of Lung Maturation and Development | Zendy

Dawn M. Simon | Zendy; Thomas J. Mariani | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Role of PPARs and Retinoid X Receptors in the Regulation of Lung Maturation and Development

Author(s) -

Dawn M. Simon,

Thomas J. Mariani

Publication year - 2007

Publication title -

ppar research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.164

H-Index - 49

eISSN - 1687-4765

pISSN - 1687-4757

DOI - 10.1155/2007/91240

Subject(s) - retinoic acid , retinoid , lung , retinoic acid receptor , receptor , medicine , retinoid x receptor , microbiology and biotechnology , tretinoin , bioinformatics , biology , cancer research , nuclear receptor , biochemistry , transcription factor , gene

Understanding lung development has significant importance to public health because of the fact that interruptions in the normal developmental processes can have prominent effects on childhood and adult lung health. It is widely appreciated that the retinoic acid (RA) pathway plays an important role in lung development. Additionally, PPARs are believed to partner with receptors of this pathway and therefore could be considered extensions of retinoic acid function, including during lung development. This review will begin by introducing the relationship between the retinoic acid pathway and PPARs followed by an overview of lung development stages and regulation to conclude with details on PPARs and the retinoic acid pathway as they may relate to lung development.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research