Colonic Squamous Cell Carcinoma in Ulcerative Colitis: Report of a Case and Review of the Literature | Zendy

Huilan Cheng | Zendy; Michael D. Sitrin | Zendy; Sateesh Satchidanand | Zendy; Jan M. Novak | Zendy

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Colonic Squamous Cell Carcinoma in Ulcerative Colitis: Report of a Case and Review of the Literature

Author(s) -

Huilan Cheng,

Michael D. Sitrin,

Sateesh Satchidanand,

Jan M. Novak

Publication year - 2007

Publication title -

canadian journal of gastroenterology

Language(s) - English

Resource type - Journals

eISSN - 1916-7237

pISSN - 0835-7900

DOI - 10.1155/2007/904081

Subject(s) - ulcerative colitis , medicine , squamous metaplasia , rectum , metaplasia , inflammatory bowel disease , pathology , basal cell , gastroenterology , carcinoma , disease , epithelium

Squamous cell carcinoma (SCC) is a rare neoplasm in the colorectum. A case of SCC rising from an area of squamous metaplasia in the rectum is presented in a patient with long-standing ulcerative colitis and perianal warts. This is the first report in the literature describing the evolution of squamous metaplasia in the colonic mucosa into invasive carcinoma over time. Related literature on colorectal SCC and squamous metaplasia, and their relationships with inflammatory bowel disease and human papilloma virus, is reviewed.

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