Experimental Study on Bioluminescence Tomography with Multimodality Fusion | Zendy

Yujie Lv | Zendy; Jie Tian | Zendy; Wenxiang Cong | Zendy; Ge Wang | Zendy

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Experimental Study on Bioluminescence Tomography with Multimodality Fusion

Author(s) -

Yujie Lv,

Jie Tian,

Wenxiang Cong,

Ge Wang

Publication year - 2007

Publication title -

international journal of biomedical imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.626

H-Index - 41

eISSN - 1687-4196

pISSN - 1687-4188

DOI - 10.1155/2007/86741

Subject(s) - a priori and a posteriori , multimodality , robustness (evolution) , computer science , tomography , computer vision , scanner , sensor fusion , finite element method , iterative reconstruction , artificial intelligence , optics , physics , philosophy , biochemistry , chemistry , epistemology , world wide web , gene , thermodynamics

To verify the influence of a priori information on the nonuniqueness problem of bioluminescence tomography (BLT), the multimodality imaging fusion based BLT experiment is performed by multiview noncontact detection mode, which incorporates the anatomical information obtained by the microCT scanner and the background optical properties based on diffuse reflectance measurements. In the reconstruction procedure, the utilization of adaptive finite element methods (FEMs) and a priori permissible source region refines the reconstructed results and improves numerical robustness and efficiency. The comparison between the absence and employment of a priori information shows that multimodality imaging fusion is essential to quantitative BLT reconstruction.

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