Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial | Zendy

Amar Nath Chatterjee | Zendy; MG Swain | Zendy; ShoeiSheng Lee | Zendy; Vincent G. Bain | Zendy; Kevork Peltekian | Zendy; Kenneth Croitoru | Zendy; P C Adams | Zendy; Kelly Kaita | Zendy; Jerome Teitel | Zendy; EJ Heathcote | Zendy

Open Access

Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial

Author(s) -

Amar Nath Chatterjee,

MG Swain,

ShoeiSheng Lee,

Vincent G. Bain,

Kevork Peltekian,

Kenneth Croitoru,

P C Adams,

Kelly Kaita,

Jerome Teitel,

EJ Heathcote

Publication year - 2007

Publication title -

canadian journal of gastroenterology

Language(s) - English

Resource type - Journals

eISSN - 1916-7237

pISSN - 0835-7900

DOI - 10.1155/2007/817198

Subject(s) - ribavirin , medicine , gastroenterology , coinfection , immunology , pegylated interferon , hepatitis c virus , body mass index , virus

Patients with congenital coagulation disorders and chronic hepatitis C virus (HCV) infection have multiple risk factors (ie, infection predominantly with genotype-1 HCV, long duration of the disease, HIV coinfection and male sex) for poor response to antiviral therapy. The present study compared induction therapy with interferon-alpha (IFN-alpha)-2b with standard IFN-alpha2b therapy. Pegylated IFN was not available at the time that the study was initiated.

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