Refractory Crohn’s Disease of the Vulva Treated with Infliximab: A Case Report | Zendy

Sapna Makhija | Zendy; Martin J. Trotter | Zendy; Elizabeth M. Wagner | Zendy; Sylvain Coderre | Zendy; Remo Panaccione | Zendy

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Refractory Crohn’s Disease of the Vulva Treated with Infliximab: A Case Report

Author(s) -

Sapna Makhija,

Martin J. Trotter,

Elizabeth M. Wagner,

Sylvain Coderre,

Remo Panaccione

Publication year - 2007

Publication title -

canadian journal of gastroenterology

Language(s) - English

Resource type - Journals

eISSN - 1916-7237

pISSN - 0835-7900

DOI - 10.1155/2007/737640

Subject(s) - medicine , refractory (planetary science) , vulva , infliximab , abdominal pain , dermatology , disease , diarrhea , crohn's disease , weight loss , gastrointestinal tract , presentation (obstetrics) , gastroenterology , surgery , obesity , physics , astrobiology

Crohn's disease (CD) is a chronic relapsing and remitting inflammatory disorder of the gastrointestinal tract. The common presentation includes abdominal pain, abdominal cramping and diarrhea. Many patients may exhibit systemic symptoms of fever and weight loss. Approximately 20% to 40% of patients will experience extraintestinal manifestations that involve the eyes, skin and joints. Women may experience a variety of gynecological manifestations, including vulvovaginal involvement, which is often not recognized and also difficult to treat. A case of refractory vulvovaginal CD is presented and the literature of gynecological manifestations of CD and its treatment are reviewed.

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