The Progress on Genetic Analysis of Nasopharyngeal Carcinoma
Author(s) -
Xiaofeng Zhou,
Jing Cui,
Virgilia Macias,
André Kajdacsy-Balla,
Hui Ye,
Jianguang Wang,
P. Nagesh Rao
Publication year - 2007
Publication title -
comparative and functional genomics
Language(s) - English
Resource type - Journals
eISSN - 1532-6268
pISSN - 1531-6912
DOI - 10.1155/2007/57513
Subject(s) - nasopharyngeal carcinoma , carcinogenesis , malignancy , genetic analysis , biology , epstein–barr virus , virus , bioinformatics , gene , medicine , genetics , radiation therapy
Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is one of the most common cancers in Southeast Asia. Both genetic and environmental factors contribute to the tumorigenesis of NPC, most notably the consumption of certain salted food items and Epstein-Barr virus infection. This review will focus on the current progress of the genetic analysis of NPC (genetic susceptibilities and somatic alterations). We will review the current advances in genomic technologies and their shaping of the future direction of NPC research.
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