Open AccessHypoxia and Angiogenesis in Endometrioid Endometrial Carcinogenesis
Author(s) -
Nicole Horrée,
Paul J. van Diest,
Petra van der Groep,
Daisy M. D. S. SieGo,
A. Peter M. Heintz
Publication year - 2007
Publication title -
analytical cellular pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.576
H-Index - 24
eISSN - 2210-7185
pISSN - 2210-7177
DOI - 10.1155/2007/434731
Subject(s) - angiogenesis , endometrium , carcinogenesis , hypoxia (environmental) , immunohistochemistry , cancer research , carcinoma , hyperplasia , microvessel , biology , pathology , neovascularization , endometrial hyperplasia , medicine , endocrinology , cancer , chemistry , organic chemistry , oxygen
Hypoxia-inducible factor 1alpha (HIF-1alpha) plays an essential role in the adaptive response of cells to hypoxia, triggering biologic events associated with aggressive tumor behavior.
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