Testing Conclusions From Functional Imaging of Working Memory with Data From Acute Stroke
Author(s) -
Lisa E. Philipose,
Hannah H. Alphs,
Vivek Prabhakaran,
Argye E. Hillis
Publication year - 2007
Publication title -
behavioural neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.859
H-Index - 48
eISSN - 1875-8584
pISSN - 0953-4180
DOI - 10.1155/2007/396946
Subject(s) - working memory , stroke (engine) , verbal memory , psychology , lateralization of brain function , spatial memory , functional imaging , neuroscience , medicine , audiology , cognition , mechanical engineering , engineering
Functional imaging studies indicate that the left hemisphere mediates verbal working memory, while the right hemisphere mediates both verbal and spatial working memory. We evaluated acute stroke patients with working memory tests and imaging to identify whether unilateral dysfunction causes deficits in spatial and/or verbal working memory deficits. While left cortical stroke patients had verbal working memory impairments (p<0.003), right cortical stroke patients had both verbal p<0.007) and spatial working memory (p<0.03) impairments, confirming functional imaging results. Patients with transient ischemic stroke and patients with non-cortical stroke did not have significant deficits in working memory in either modality.
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