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Treatment Strategy: Role of Enfuvirtide in Managing Treatment-Limiting Side Effects
Author(s) -
Christos Tsoukas
Publication year - 2007
Publication title -
canadian journal of infectious diseases and medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 38
eISSN - 1918-1493
pISSN - 1712-9532
DOI - 10.1155/2007/198172
Subject(s) - enfuvirtide , limiting , medicine , intensive care medicine , pharmacology , immunology , antibody , gp41 , engineering , epitope , mechanical engineering
Side effects can limit the options available to physicians for the treatment of HIV infection. Management of these side effects is essential, to avoid cessation of treatment. The entry inhibitor enfuvirtide can be useful as one of three active agents in an HIV treatment regimen as a way to both reduce treatment-limiting side effects and provide an efficacious agent for viral control. In the present case, the patient had a problematic and lengthy treatment history, with numerous concomitant conditions. His latest regimen, which includes an agent in a new drug class (enfuvirtide), has maintained HIV suppression while minimizing toxicity

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