HPV Detection Methods | Zendy

Antoinette A. T. P. Brink | Zendy; Peter J.F. Snijders | Zendy; Chris J.L.M. Meijer | Zendy

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HPV Detection Methods

Author(s) -

Antoinette A. T. P. Brink,

Peter J.F. Snijders,

Chris J.L.M. Meijer

Publication year - 2007

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/2007/147429

Subject(s) - cervical intraepithelial neoplasia , genotyping , cervical cancer , human papillomavirus , cytology , medicine , gynecology , cervical screening , papillomaviridae , obstetrics , cervical cancer screening , oncology , cancer , pathology , biology , genotype , gene , biochemistry

Given the causal relation between a persistent high-risk human papillomavirus (hrHPV) infection and the development of high-grade cervical intraepithelial neoplasia (CIN) and cervical cancer, hrHPV testing has been advocated in addition to cytology for the detection of clinically relevant cervical lesions. HrHPV testing is thought to improve cervical screening algorithms, the management of women with cytologically equivocal smears, and the management of women treated for high grade CIN. In this chapter we discuss different methods for HPV detection and genotyping and their respective applications.

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