Effects of Hydrofluoroalkane and Dry Powder‐Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients | Zendy

HansPeter Hauber | Zendy; Rame Taha | Zendy; Céline Bergeron | Zendy; Vladimir Migounov | Zendy; Qutayba Hamid | Zendy; Ron Olivenstein | Zendy

Open Access

Effects of Hydrofluoroalkane and Dry Powder‐Formulated Corticosteroids on Sputum Inflammatory Markers in Asthmatic Patients

Author(s) -

HansPeter Hauber,

Rame Taha,

Céline Bergeron,

Vladimir Migounov,

Qutayba Hamid,

Ron Olivenstein

Publication year - 2006

Publication title -

canadian respiratory journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.675

H-Index - 53

eISSN - 1916-7245

pISSN - 1198-2241

DOI - 10.1155/2006/648392

Subject(s) - medicine , sputum , placebo , budesonide , asthma , corticosteroid , gastroenterology , dry powder inhaler , inhalation , interleukin 8 , immunology , inflammation , anesthesia , pathology , inhaler , tuberculosis , alternative medicine

Inhaled corticosteroids are powerful drugs that can suppress airway inflammation in asthmatic patients. Deposition of most of the inhaled corticosteroid occurs mainly in the central airways. However, a new hydrofluoroalkane formulation of beclomethasone dipropionate (HFA-BDP) is preferentially deposited in the distal airways. Inflammatory characteristics of induced sputum have been shown to differ in samples collected early after sputum induction compared with later.

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