Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations | Zendy

Srinubabu Gedela | Zendy; B. Sudha Rani | Zendy; J. V. L. N. Seshagiri Rao | Zendy

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Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations

Author(s) -

Srinubabu Gedela,

B. Sudha Rani,

J. V. L. N. Seshagiri Rao

Publication year - 2006

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2006/643624

Subject(s) - hydrochloric acid , ziprasidone , chromatography , dosage form , chemistry , organic chemistry , computer science , schizophrenia (object oriented programming) , clozapine , programming language

A simple and reproducible spectrophotometric method has been developed for the determination of Ziprasidone hydrochloride monohydrate (ZPS) in bulk and in dosage forms. The method is based on the extraction of the drugs into organic layer of the dye TPooo in presence of 0.1 N hydrochloric acid and the absorbances were measured at 490 nm. Results indicate that the proposed method was simple, sensitive, accurate and reproducible.

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