Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry | Zendy

Praveen Kumar | Zendy; P. Bhanu Prakash | Zendy; M. Murali Krishna | Zendy; M. Santha Yadav | Zendy; C. Asha Deepthi | Zendy

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Simultaneous Estimation of Domperidone and Pantoprazole in Solid Dosage Form by UV Spectrophotometry

Author(s) -

Praveen Kumar,

P. Bhanu Prakash,

M. Murali Krishna,

M. Santha Yadav,

C. Asha Deepthi

Publication year - 2006

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2006/640731

Subject(s) - domperidone , pantoprazole , dosage form , chromatography , spectrophotometry , chemistry , medicine , pharmacology , omeprazole , dopamine

Domperidone is an antiemetic and pantoprazole is an antiulcer drug. Simple, precise, rapid and selective simultaneous equation and Q- analysis UV spectrophotometric methods have been developed for the simultaneous determination of domperidone and pantoprazole from combined tablet dosage forms. The methods involve solving of simultaneous equations and Q-value analysis based on measurement absorptivity at 216, 287 and 290 nm respectively. Linearity lies between 1-15 mcg/mL for domperidone and 0-50 mcg/mL for pantoprazole.

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