C242T Polymorphism in CYBA Gene (p22phox) and Risk of Coronary Artery Disease in a Population of Caucasian Italians
Author(s) -
Sabisti,
Paolo Spallarossa,
Paola Altieri,
Silvano Garibaldi,
Patrizia Fabbi,
Luisa Polito,
Luca Bacino,
Michele Brunelli,
Claudio Brunelli,
Antonio Barsotti,
G Ghigliotti
Publication year - 2006
Publication title -
disease markers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.912
H-Index - 66
eISSN - 1875-8630
pISSN - 0278-0240
DOI - 10.1155/2006/458587
Subject(s) - coronary artery disease , medicine , population , nadph oxidase , stenosis , allele , genotype , coronary arteries , allele frequency , coronary atherosclerosis , cardiology , single nucleotide polymorphism , gastroenterology , endocrinology , oxidative stress , artery , biology , gene , genetics , environmental health
specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. Some studies have identified a relationship between progression of atherosclerosis and C242T mutation in CYBA gene coding for p22phox, a subunit of the NADH/NADPH oxidase system.
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