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The American Thoracic Society’s Spirometric Criteria Alone is Inadequate in Asthma Diagnosis
Author(s) -
John Gjevre,
Thomas S. Hurst,
Regina M. TaylorGjevre,
Donald W. Cockcroft
Publication year - 2006
Publication title -
canadian respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.675
H-Index - 53
eISSN - 1916-7245
pISSN - 1198-2241
DOI - 10.1155/2006/198940
Subject(s) - medicine , spirometry , asthma , pulmonary function testing , bronchodilator , gold standard (test) , physical examination , vital capacity , bronchial hyperresponsiveness , physical therapy , respiratory disease , lung function , diffusing capacity , lung
The diagnosis of asthma is based on clinical symptoms, physical examination and pulmonary function tests, and can be very challenging. Most patients with asthma have a significant postbronchodilator response on spirometry indicating airway hyperresponsiveness. However, having a significant bronchodilator response by itself is not diagnostic of asthma. The definition of a 'significant' response has also been controversial. Many respirologists use the American Thoracic Society (ATS) postbronchodilator response criteria of 12% (provided it is 200 mL or greater) improvement in forced expiratory volume in 1 s (or forced vital capacity) from the baseline spirometry.

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