Clinical Application of Rapid Assay of Interleukin‐6 in Influenza‐Associated Encephalopathy | Zendy

Mikage Nakamura | Zendy; Gaku Yamanaka | Zendy; Hisashi Kawashima | Zendy; Yoshiaki Watanabe | Zendy; Hiroaki Ioi | Zendy; Yasuyo Kashiwagi | Zendy; Kouji Takekuma | Zendy; Akinori Hoshika | Zendy; Mizuho Hayakawa | Zendy; Shigeru Suzuki | Zendy

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Clinical Application of Rapid Assay of Interleukin‐6 in Influenza‐Associated Encephalopathy

Author(s) -

Mikage Nakamura,

Gaku Yamanaka,

Hisashi Kawashima,

Yoshiaki Watanabe,

Hiroaki Ioi,

Yasuyo Kashiwagi,

Kouji Takekuma,

Akinori Hoshika,

Mizuho Hayakawa,

Shigeru Suzuki

Publication year - 2005

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/2005/671609

Subject(s) - medicine , interleukin , encephalopathy , virology , interleukin 1β , immunology , pathology , cytokine

The characteristics of influenza-associated encephalopathy is the high mortality and nimble progress with coma which appears in general cases within 48 hours. Most of patients show no abnormalities in the standard blood checks on admission or in early stage. In this study we investigated if a rapid assay of interleukin (IL)-6 is useful in influenza-associated encephalopathy in early stages. The levels of IL-6 in patients with influenza-associated encephalopathy did not show any significant difference compared with those in patients with febrile convulsion and rotavirus-associated convulsion. However the levels of IL-6 in severe cases were significantly higher than those of mild cases with influenza-associated encephalopathy. Consequently the rapid assay of serum IL-6 is useful to evaluate and decide the therapies.

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