The Role of Gemcitabine in the Treatment of Cholangiocarcinoma and Gallbladder Cancer: A Systematic Review
Author(s) -
B. Dingle,
R. Bryan Rumble,
Melissa Brouwers
Publication year - 2005
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/2005/565479
Subject(s) - gemcitabine , medicine , gallbladder cancer , capecitabine , oncology , guideline , gallbladder , cancer , randomized controlled trial , chemotherapy , gastrointestinal cancer , radiation therapy , clinical trial , general surgery , colorectal cancer , pathology
Cholangiocarcinoma and gallbladder cancer are difficult to treat curatively. The treatment of choice is surgery, dependent on detection at a resectable stage. No chemotherapy or radiotherapy options have shown substantial activity. Gemcitabine has demonstrated response in similar cancers. Considering the lack of treatment options for cholangiocarcinoma and gallbladder cancer, a systematic review of the evidence on gemcitabine use for these indications was performed.
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