Different Profile of Interleukin-10 Production in Circulating T Cells from Atopic Asthmatics Compared with Healthy Subjects | Zendy

Koichiro Matsumoto | Zendy; Shintaro Narita | Zendy; Tracy Rerecich | Zendy; DP Snider | Zendy; Paul M. O’Byrne | Zendy

Open Access

Different Profile of Interleukin-10 Production in Circulating T Cells from Atopic Asthmatics Compared with Healthy Subjects

Author(s) -

Koichiro Matsumoto,

Shintaro Narita,

Tracy Rerecich,

DP Snider,

Paul M. O’Byrne

Publication year - 2004

Publication title -

canadian respiratory journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.675

H-Index - 53

eISSN - 1916-7245

pISSN - 1198-2241

DOI - 10.1155/2004/710962

Subject(s) - ionomycin , medicine , peripheral blood mononuclear cell , immunology , cd8 , cd3 , stimulation , asthma , endocrinology , antigen , biology , in vitro , biochemistry

Interleukin (IL)-10 is a pleiotropic cytokine released from various cells, including T cells. Although IL-10 is suggested to inhibit allergic responses, its role in asthma remains uncertain. The purpose of the present study was to compare the profile of IL-10 in circulating T cells from stable atopic asthmatics, atopic nonasthmatics and healthy controls.

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