In Vivo Measurement of Phosphorous Markers of Disease | Zendy

Fernando AriasMendoza | Zendy; Truman R. Brown | Zendy

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In Vivo Measurement of Phosphorous Markers of Disease

Author(s) -

Fernando AriasMendoza,

Truman R. Brown

Publication year - 2004

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/2004/419095

Subject(s) - in vivo , computational biology , biology , genetics

Phosphorus Magnetic Resonance Spectroscopy (31P-MRS) has been utilized to study energy, carbohydrate, and phospholipid metabolism in vitro and in vivo in live tissues non-invasively. Despite its lack of sensitivity, its application has extended to in situ human tissues and organs since proper signal localization was devised. Follow-up of phosphocreatine in neuromuscular diseases and schizophrenia and follow-up of phospholipid-related molecules in tumors are described here to demonstrate the value of 31P-MRS as an imaging technique to determine in vivo markers of disease and in the diagnosis, prognosis, and follow-up of human diseases.

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