Biosensors based on nucleic acid interaction
Author(s) -
Maria Minunni
Publication year - 2003
Publication title -
journal of spectroscopy
Language(s) - English
Resource type - Journals
eISSN - 2314-4920
pISSN - 2314-4939
DOI - 10.1155/2003/896705
Subject(s) - nucleic acid , biosensor , dna , surface plasmon resonance , organism , nanotechnology , chemistry , nucleic acid detection , computational biology , hybridization probe , nucleic acid quantitation , combinatorial chemistry , biochemistry , materials science , biology , genetics , nanoparticle
DNA sensing is an emerging technology based on hybridisation reaction between an immobilised DNA probe and a molecular target, consisting of a probe complementary sequence in solution. Many application have been developed in the field of environmental, food and clinical analysis. Surface plasmon resonance and piezoelectric sensing are reported as transduction principles for DNA-based devices. These techniques are able to monitor in real-time and without the use of any label the hybridisation reaction between nucleic acids. Particular attention is given to Genetically Modified Organism detection.
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