Quantification of urine 17-ketosteroid sulfates and their age correlations | Zendy

Qi Jia | Zendy; Mei-Feng Hong | Zendy; Zhaoxing Pan | Zendy; Cheryl Ritter | Zendy; Susan Vance | Zendy; Miriam Cortes-Guzman | Zendy; Stephen Cherniske | Zendy

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Quantification of urine 17-ketosteroid sulfates and their age correlations

Author(s) -

Qi Jia,

Mei-Feng Hong,

Zhaoxing Pan,

Cheryl Ritter,

Susan Vance,

Miriam Cortes-Guzman,

Stephen Cherniske

Publication year - 2002

Publication title -

journal of spectroscopy

Language(s) - English

Resource type - Journals

eISSN - 2314-4920

pISSN - 2314-4939

DOI - 10.1155/2002/835987

Subject(s) - ketosteroid , dehydroepiandrosterone , urine , chemistry , endocrinology , medicine , creatinine , dehydroepiandrosterone sulfate , urinary system , chromatography , steroid , morning , renal function , biology , androgen , enzyme , biochemistry , hormone , isomerase

Dehydroepiandrosterone (DHEA) is a steroid secreted primarily by the adrenal gland and plays an important role as the primary precursor of many important sex steroids. The negative correlation between age and the secretion of DHEA (I) and in its sulfate form (II, DHEA-S) has been documented in human studies. Serum DHEA (I) and/or DHEA-S (II) levels have been associated with central nervous system function, immunity, cardiovascular functions, insulin sensitivity, and body composition.

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