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Analysis of Expression Patterns: The Scope of the Problem, the Problem of Scope
Author(s) -
Yidong Chen,
Zohar Yakhini,
Amir BenDor,
Edward R. Dougherty,
Jeffrey M. Trent,
Michael Bittner
Publication year - 2001
Publication title -
disease markers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.912
H-Index - 66
eISSN - 1875-8630
pISSN - 0278-0240
DOI - 10.1155/2001/728649
Subject(s) - scope (computer science) , dna microarray , expression (computer science) , computational biology , biology , data science , sample (material) , computer science , gene expression , gene , genetics , chemistry , chromatography , programming language
Studies of the expression patterns of many genes simultaneously lead to the observation that even in closely related pathologies, there are numerous genes that are differentially expressed in consistent patterns correlated to each sample type. The early uses of the enabling technology, microarrays, was focused on gathering mechanistic biological insights. The early findings now pose another clear challenge, finding ways to effectively use this kind of information to develop diagnostics.

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