English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

A retrospective cohort study of 79 patients with chronic  hepatitis C was performed to assess the predictive nature of  various variables (age, sex, route of transmission, extent of  steatosis, alcohol consumption and serum aminotransferase  values), with the underlying hepatic histopathology. The  newly modified Knodell histological activity index by  Desmet et al (1), which separately scores the inflammation  from the fibrosis on the liver biopsy, was used. Using stepwise  multivariate logistic regression, it was discovered that  serum aspartate aminotransferase (AST) values had a predictive  relationship with overall histological activity  (r=0.62), portal inflammation (r=0.58), piecemeal necrosis  (r=0.61) and extent of hepatic fibrosis (r=0.64). Serum  AST values correctly predicted the inflammatory grade in  63 of 79 (80%) patients, and the fibrosis stage in 50 of 79  (63%) patients - higher than the predictive values of ALT.  Serum alanine aminotransferase (ALT) values did not correlate  with the degree of histological inflammation (r=0.39)  but did correlate mildly with the extent of hepatic fibrosis  (r=0.51). There were no significant correlations of the  other variables with histological inflammation or fibrosis

Liver Enzymes as Surrogate Markers of Hepatitis C Histopathology – Avoiding the Liver Biopsy Needle?