Association of Epstein‐Barr Virus with Human Mammary Carcinoma. Pros and Cons | Zendy

Robert Touitou | Zendy; Mathilde Bonnet | Zendy; Irène Joab | Zendy

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Association of Epstein‐Barr Virus with Human Mammary Carcinoma. Pros and Cons

Author(s) -

Robert Touitou,

Mathilde Bonnet,

Irène Joab

Publication year - 2001

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/2001/649807

Subject(s) - epstein–barr virus , virus , biology , lymph , breast carcinoma , genome , carcinoma , mammary gland , pathology , cancer research , nasopharyngeal carcinoma , breast cancer , virology , cancer , gene , medicine , genetics , radiation therapy

The Epstein-Barr virus (EBV) is associated with the development of different malignancies. In the last few years, EBV has been detected in a subset of breast tumors. The EBV genome was detected by PCR and Southern-blot analysis and identification of the infected cells was determined using different in situ methods. EBV has detected more frequently in steroid hormone receptors negative tumors, in high histological SBR grade tumors and furthermore, the EBV genome was also observed in metastatic lymph nodes, along with EBV detection in the primary tumor. Opposing results are discussed.

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