Acute Hepatitis Induced by Alpha-Interferon in a Patient with Chronic Hepatitis C | Zendy

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Acute Hepatitis Induced by Alpha-Interferon in a Patient with Chronic Hepatitis C

Author(s) -

I Kraus,

Dinko Vitezić

Publication year - 2001

Publication title -

canadian journal of gastroenterology

Language(s) - English

Resource type - Journals

eISSN - 1916-7237

pISSN - 0835-7900

DOI - 10.1155/2001/510742

Subject(s) - medicine , hepatitis , acute hepatitis , alpha interferon , interferon , jaundice , chronic hepatitis , hepatitis c , immunology , alpha (finance) , gastroenterology , virology , surgery , virus , construct validity , patient satisfaction

Hepatic adverse effects occur very rarely with alpha-interferon therapy. A case of acute hepatitis induced by alpha-interferon in a 33-year-old man with chronic hepatitis C is described. The patient developed acute hepatitis with very high aminotransferase activity and jaundice. After discontinuing alpha-interferon therapy, hepatitis resolved rapidly. The immune-mediated mechanism is the most probable cause of this hepatitis.

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