Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno‐Histochemistry and Tv Image Cytometry | Zendy

Erika Szaleczky | Zendy; László Prónai | Zendy; Béla Molnár | Zendy; Lajos Berczi | Zendy; János Fehér | Zendy; Zsolt Tulassay | Zendy

Open Access

Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno‐Histochemistry and Tv Image Cytometry

Author(s) -

Erika Szaleczky,

László Prónai,

Béla Molnár,

Lajos Berczi,

János Fehér,

Zsolt Tulassay

Publication year - 2000

Publication title -

analytical cellular pathology

Language(s) - English

Resource type - Journals

eISSN - 2210-7185

pISSN - 2210-7177

DOI - 10.1155/2000/830906

Subject(s) - chronic gastritis , proliferating cell nuclear antigen , helicobacter pylori , intestinal metaplasia , gastroenterology , proliferation index , immunohistochemistry , gastritis , medicine , atrophic gastritis , flow cytometry , ki 67 , pathology , immunology

[corrected] Epithelial cell proliferation activity has been reported both to be unaltered and increased in Helicobacter pylori (H. pylori) associated chronic gastritis. The proliferation rate decreased following H. pylori eradication, but results are controversial whether this change is dependent on the success of eradication. We compared the cell proliferation activity of H. pylori positive and negative gastric epithelial biopsies in chronic gastritis with and without intestinal metaplasia (IM) and gastric cancer by the expression of proliferation cell nuclear antigen (PCNA) and Tv image cytometry, and assessed the effect of H. pylori eradication on the cell proliferation rate in the gastric epithelium.

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