Analysis of HMPAO SPECT Scans in Head Injury Using Statistical Parametric Mapping | Zendy

Emmanuel A. Stamatakis | Zendy; Lindsay Wilson | Zendy; D. Wyper | Zendy

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Analysis of HMPAO SPECT Scans in Head Injury Using Statistical Parametric Mapping

Author(s) -

Emmanuel A. Stamatakis,

Lindsay Wilson,

D. Wyper

Publication year - 2000

Publication title -

behavioural neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.859

H-Index - 48

eISSN - 1875-8584

pISSN - 0953-4180

DOI - 10.1155/2000/681916

Subject(s) - statistical parametric mapping , nuclear medicine , statistical analysis , parametric statistics , spect imaging , blood flow , head injury , cerebral blood flow , medicine , computer science , artificial intelligence , radiology , mathematics , magnetic resonance imaging , surgery , cardiology , statistics

The paper examines the ability of Statistical Parametric Mapping (SPM) to contribute towards the quantitative analysis of HMPAO SPECT images containing lesions. A validation study is described in which SPECT images were created that contained synthetic lesions and were analysed with SPM. The study established a set of guidelines concerning the alignment, smoothing, and statistical analysis of images. These were then applied to analysis of SPECT scans from head injured patients. A demonstration is given of the use of SPM to identify localised blood flow abnormalities associated with cognitive deficits after head injury. Correlations between blood flow abnormalities and a test of visual memory are illustrated.

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