Gastric Carcinoid Tumours and Pernicious Anemia: Case Report and Review of the Literature | Zendy

Sarah Hagarty | Zendy; I Hüttner | Zendy; Henry R. Shibata | Zendy; S S Katz | Zendy

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Gastric Carcinoid Tumours and Pernicious Anemia: Case Report and Review of the Literature

Author(s) -

Sarah Hagarty,

I Hüttner,

Henry R. Shibata,

S S Katz

Publication year - 2000

Publication title -

canadian journal of gastroenterology

Language(s) - English

Resource type - Journals

eISSN - 1916-7237

pISSN - 0835-7900

DOI - 10.1155/2000/645639

Subject(s) - pernicious anemia , carcinoid tumour , medicine , gastrin , anemia , gastroenterology , fundus (uterus) , stomach , atrophic gastritis , pernicious anaemia , gastritis , surgery , secretion

Patients with pernicious anemia are at risk of developing carcinoid tumours of the stomach. A patient with pernicious anemia and multifocal carcinoid tumours of the gastric fundus that regressed after antrectomy is presented. The frequent occurrence of gastric carcinoid tumours in patients with long-standing pernicious anemia suggests that surveillance gastroscopy and biopsies of the fundus might be indicated. Compete functional antrectomy may effectively cause these tumours to regress by removing their excessive gastrin hormonal stimulation. However, incomplete antrectomy can result in persistently elevated serum gastrin and failure of total disappearance of the carcinoid tumours.

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