Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance | Zendy

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Transposons and Integrons: Natural Genetic Engineering of Bacterial Resistance

Author(s) -

Paul H. Roy

Publication year - 1999

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/1999/619276

Subject(s) - biology , transposable element , antibiotic resistance , mobile genetic elements , genetics , bacteria , dna transposable elements , computational biology , gene , plasmid , genome

The advent of antibiotics in clinical medicine has resulted in theemergence of multiresistant strains of bacteria. Bacteria possesssophisticated mechanisms of genetic exchange that have driventheir recent evolution. Among these are transposons and integrons,the latter having interesting parallels with genetic engineeringtechniques used in the laboratory. An understanding of thesemechanisms through studies of the molecular basis of thedissemination of resistance genes will aid rational choices inantibiotic therapy

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