Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing | Zendy

Jerome J. Schentag | Zendy

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Grepafloxacin in Patients with Acute Bacterial Exacerbations of Chronic Bronchitis - a Question of Speed in Bacterial Killing

Author(s) -

Jerome J. Schentag

Publication year - 1998

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/1998/407350

Subject(s) - medicine , chronic bronchitis , sputum , pharmacodynamics , bronchitis , pharmacokinetics , minimum inhibitory concentration , area under the curve , antibiotics , population , sputum culture , gastroenterology , pharmacology , tuberculosis , microbiology and biotechnology , biology , pathology , environmental health

OBJECTIVE: To characterize the population pharmacokinetics and pharmacodynamics of oral grepafloxacin in patients with acute bacterial exacerbations of chronic bronchitis (ABECB), with particular attention to the speed of bacterial killing. This was possible because the study design incorporated daily cultures of the patients’ sputum

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