Particulate Air Pollution and Health: Emerging Issues and Research Needs Related to the Development of Air Quality Standards

The health effects of particulate air pollution were highlighted at the Eighth Annual Conference of the International Society for Environmental Epidemiology, held in Edmonton, Alberta in August 1996. Despite consistent evidence for adverse respiratory and cardiovascular health effects related to particulate air pollution, there are significant gaps in the knowledge of the mechanisms whereby particulate air pollution affects human health. Questions regarding the appropriate measure of dose for assessing exposures relevant to health outcomes and the methods used to analyze dose-response data remain unanswered. Health effects have been demonstrated across the range of exposures that have been examined, and further research in low exposure settings is necessary to explore the lower end of the dose-response curve. Although a significant body of literature has been generated, comprehensive risk assessments have not been undertaken. Examination of the chronic effects of particulate air pollution and identification of high risk populations are necessary. Although there are significant unanswered questions regarding the health effects of particulate air pollution, the available information suggests that particulate air pollution at levels consistent with current standards is associated with measurable health effects