Chronic Pancreatitis and Neoplasia: Correlation or Coincidence | Zendy

George N. Zografos | Zendy; Asher Bean | Zendy; M. J. Bowles | Zendy; R C N Williamson | Zendy

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Chronic Pancreatitis and Neoplasia: Correlation or Coincidence

Author(s) -

George N. Zografos,

Asher Bean,

M. J. Bowles,

R C N Williamson

Publication year - 1997

Publication title -

hpb surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.561

H-Index - 26

eISSN - 1607-8462

pISSN - 0894-8569

DOI - 10.1155/1997/89374

Subject(s) - medicine , pancreatitis , incidence (geometry) , gastroenterology , pancreatic carcinoma , pancreas , pathology , pancreatic cancer , cancer , physics , optics

Any link between pancreatic carcinoma and chronic pancreatitis could reflect the malignant potential of a chronic inflammatory process. Four patients with ductal adenocarcinomas had a long history of pancreatic pain (median duration 5 years) and showed clear-cut evidence of chronic pancreatitis "downstream" of the tumour. Four were alcoholics and two heavy smokers. These four cases arose within a surgical series of approximately 250 patients with chronic pancreatitis, giving an incidence of 1.6 per cent. The incidence and anatomical distribution of carcinoma and chronic pancreatitis could possibly be consistent with a casual relationship.

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