Nesidioblastosis in the Adult Surgical Management | Zendy

J P Garcia | Zendy; T Franca | Zendy; Consiglieri Pedroso | Zendy; Carlos Cardoso | Zendy; M′Olímpia Cid | Zendy

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Nesidioblastosis in the Adult Surgical Management

Author(s) -

J P Garcia,

T Franca,

Consiglieri Pedroso,

Carlos Cardoso,

M′Olímpia Cid

Publication year - 1997

Publication title -

hpb surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.561

H-Index - 26

eISSN - 1607-8462

pISSN - 0894-8569

DOI - 10.1155/1997/81239

Subject(s) - nesidioblastosis , medicine , pancreatectomy , pancreas , hyperinsulinemic hypoglycemia , immunohistochemistry , endocrine system , pathology , surgical pathology , general surgery , insulinoma , hypoglycemia , insulin , hormone

Nesidioblastosis is an exceedingly rare occurrence in the adult and, when it appears, it is usually part of a MEA1 syndrome. We present a case of nesidioblastosis in a young woman, with no concurrent endocrine pathology, while we discuss in detail the diagnostic and therapeutic problems posed by this condition. The selected treatment was sub-total pancreatectomy (70-80%) and the histopathologic and immunohistochemical tests of the surgical specimen showed: "Diffuse Nesidioblastosis". The histopathologic and immuno-histochemical features of the resected pancreas are analysed in detail.

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