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Oxidations performed on four indolic bases, β-carboline 1, ibogaine 2, reserpine 3 and ajmaline 4, by hepatic cytochrome P450 (Cyt. P450) and ferrous picolinate (Fe(PA)2), lead to alicyclic hydroxylation as major reaction products.

Oxidation of indolic bases by cytochrome P450 and ferrous picolinate