Association of Human Lymphocyte Antigens with Obstructive Airways Disease after Bone Marrow Transplantation
Author(s) -
David Spaner,
Jeffrey H. Lipton,
Charles K. Chan
Publication year - 1996
Publication title -
canadian respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.675
H-Index - 53
eISSN - 1916-7245
pISSN - 1198-2241
DOI - 10.1155/1996/540635
Subject(s) - medicine , human leukocyte antigen , transplantation , histocompatibility , immunology , etiology , population , retrospective cohort study , bone marrow , lung transplantation , antigen , environmental health
BACKGROUND: Obstructive airways disease (OAD) is a known complication of allogeneic bone marrow transplantation. The etiology of OAD is unknown but is probably multifactorial. The identification of a significant human lymphocyte antigen (HLA) association with the development of OAD might offer some insight into its pathogenesis and serve as a marker to identify prospectively patients at risk for developing OAD
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