Cathepsin-D And Tnf-α in Bladder Cancer | Zendy

Tarek Salman | Zendy; O. El-Ahmady | Zendy; maram el-shafee | Zendy; Sherif Omar | Zendy; Isam Noori Salman | Zendy

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Cathepsin-D And Tnf-α in Bladder Cancer

Author(s) -

Tarek Salman,

O. El-Ahmady,

maram el-shafee,

Sherif Omar,

Isam Noori Salman

Publication year - 1996

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/1996/250191

Subject(s) - bladder cancer , tumor necrosis factor alpha , cathepsin d , medicine , cathepsin , lymph node , cancer , urinary bladder cancer , cathepsin l , pathology , cathepsin b , urinary system , oncology , urinary bladder , biology , enzyme , biochemistry

In a study of 34 normal healthy controls, 35 patients with urinary tract bilharziasis and 93 bladder cancer patients (62 of them are operable cases and 31 are non-operable ones), serum tumor necrosis factor alpha (TNF-alpha) and cytosolic Cathepsin-D were estimated. Though both potential markers were elevated in bladder cancer patients, neither Cathepsin-D nor TNF-alpha showed associations of prognostic value since there were no positive correlations with tumor stages, grades or association of tumors with bilharzial ova or lymph node involvement.

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