Intra- and Interlaboratory Reproducibility of an ELISA Serological Test for Lyme Disease
Author(s) -
Martin C. Tammemägi,
John Frank,
Michael LeBlanc,
Harvey Artsob
Publication year - 1994
Publication title -
canadian journal of infectious diseases and medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1918-1493
pISSN - 1712-9532
DOI - 10.1155/1995/626945
Subject(s) - lyme disease , medicine , reproducibility , serology , kappa , cohen's kappa , immunology , statistics , antibody , mathematics , geometry
Lyme disease has been increasingly diagnosed throughout North America since the late 1970s. The clinical diagnosis and epidemiological monitoring of Lyme disease are aided by serological testing for the etiological agent, Borrelia burgdorferi. Numerous authorities have questioned the reproducibility of these serological tests. This study assessed the intra- and interlaboratory reproducibility of an elisa used to aid in the diagnosis of Lyme disease.
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