Wilson’s Disease in an Elderly Patient
Author(s) -
Maziar Badii,
H.C. George Wong,
Urs P. Steinbrecher,
Hugh James Freeman
Publication year - 1995
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/1995/352692
Subject(s) - wilson's disease , ceruloplasmin , fleischer , disease , medicine , copper metabolism , chronic liver disease , liver disease , urine , gastroenterology , pathology , copper , chemistry , cirrhosis , archaeology , organic chemistry , german , history
A 65-year-old man with Fanconi’s syndrome was investigated for the cause of chronic liver disease. Wilson’s disease was diagnosed based on the detection of bilateral Kayser-Fleischer rings, a low serum ceruloplasmin level, increased urine copper excretion and positive histochemical stains of his liver for copper. This case is unusual because of the patient’s elderly age at the time of diagnosis and the absence of neurological changes due to Wilson’s disease in spite of advanced hepatic disease and the presence of Kayser-Fleischer rings. Even in the elderly patient, Wilson’s disease should be considered a possible cause of chronic liver disease
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